CASCADE
Cognitive And Social Consequences of mild Auditory loss in DEvelopment...
Description
The CASCADE project aims to investigate how early-onset alterations in auditory input are associated with changes in social and cognitive behavior and identify the neurobiological processes that may contribute to these outcomes. By combining compleme...
General Design
- Type
- Preclinical study
- Design
- Cross-sectional
- Start/End data collection
- 2019 until 2026
- PID
- https://doi.org/10.34760/6a69ef00bbbef
Population
- Main medical condition
- VIII Diseases of the ear and mastoid process
- H80-H83 Diseases of inner ear
- H83.3 Noise effects on inner ear
- H90-H95 Other disorders of ear
- H90.0 Conductive hearing loss, bilateral
- H90.3 Sensorineural hearing loss, bilateral
- H90.6 Mixed conductive and sensorineural hearing loss, bilateral
- H91.9 Hearing loss, unspecified
- XVI Certain conditions originating in the perinatal period
- P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
- P04.1 Fetus and newborn affected by other maternal medication
Organisations
Lead organisations
- University Medical Center Groningen (UMCG)Netherlands (the)https://www.umcg.nl
Data originator, Data holder, Data provider, Researcher, Data access provider
Additional organisations
Contributors
- prof. dr. S.J. (Sonja) PyottUniversity Medical Center Groningens.pyott@umcg.nl
Principal Investigator, Primary contact
Available Data & Samples
Data categories
- Biological samples
- Imaging data
- Physiological/Biochemical measurements
- Other
Sample categories
- Tissue (FFPE)
- Nervous System - Tissue (FFPE)
- Brain - Tissue (FFPE)
- Brain Stem - Tissue (FFPE)
- Sense Organs - Tissue (FFPE)
- Ear - Tissue (FFPE)
- Tissue (Frozen)
- Nervous System - Tissue (Frozen)
- Brain - Tissue (Frozen)
- Cerebellum - Tissue (Frozen)
Areas of information
- Symptoms and signs
- Symptoms and signs involving cognition, perception, emotional state and behaviour (R40-R46)
- Physical measures and assessments
- Brain and nerves
- Cognition, personality and psychological measures and assessments
- Cognitive functioning
- Social environment and relationships
- Social participation
Subpopulations
List of subpopulations for this resource...
| Name | Description | Number of participants | |
|---|---|---|---|
No results for current selection |
Collection events
List of collection events defined for this resource...
| Name | Description | Participants | Start end year | |
|---|---|---|---|---|
No results for current selection |
Publications
Animal models of early-onset hearing loss: A systematic review of the effects on cognition, social behavior, vocalization, and neurobiological mechanisms
Perinatal Fluoxetine Exposure Has No Major Effect on Myelin-Associated Glycoprotein and Myelin Basic Protein Levels in Auditory Brain Regions
Slight and hidden hearing loss differentially affect short- and long-term memory in young rats
Slight and hidden hearing loss in young rats is associated with impaired recognition memory and reduced myelination in the corpus callosum
Access conditions
Data will be made available upon request....
- Data access conditions
- no restriction
- Data use conditions
- collaboration required
- Data access fee
- false