TransplantLines

TransplantLines Biobank and Cohort Study...

Description

Prospective biobank and cohort study aimed to improve health after organ transplantation and donation. Next to biomaterial collection, the study focuses on physical and cognitive functioning and patient-reported outcome measures, such as quality of l...

General Design

More than 3,500 participants (transplant recipients and living kidney/liver donors) were included, but inclusion is ongoing. Depending on time of enrollment, patients have only one study visit, or multiple visits before and after transplantation....

Cohort type

Clinical cohort, Biobank

Design

Longitudinal

Design description

More than 3,500 participants (transplant recipients and living kidney/liver donors) were included, but inclusion is ongoing. Depending on time of enrollment, patients have only one study visit, or multiple visits before and after transplantation.

Design schematic
Design schematic
Collection type

Retrospective, Prospective

Start/End year

2015 - ongoing

Population

Netherlands (the)

Number of participants

3500

Number of participants with samples

3500

Age group at inclusion

Adult (18+ years)

Main medical condition
  • XIV Diseases of the genitourinary system
  • XI Diseases of the digestive system
  • X Diseases of the respiratory system
  • IV Endocrine, nutritional and metabolic diseases
  • IX Diseases of the circulatory system
Marker paper
Rationale and design of TransplantLines: a prospective cohort study and biobank of solid organ transplant recipients
PID

https://doi.org/10.34760/5f5b80abd0b30

Contact and Contributors

Available Data & Samples

Sample categories

  • Fluids and Secretions
  • Tissue (Frozen)
  • Tissue (FFPE)
  • Genetic material

Areas of information

  • Laboratory measures
  • Socio-demographic and economic characteristics
  • Lifestyle and behaviours
  • Perception of health, quality of life, development and functional limitations
  • Medication and supplements
  • Death
  • Cognition, personality and psychological measures and assessments
  • Administrative information
  • Social environment and relationships

Subpopulations

List of subcohorts or subpopulations for this resource...

Collection events

List of collection events defined for this resource...

Access conditions

A data and sample request form can be obtained by sending an e-mail to datarequest.transplantlines@umcg.nl. The completed form can be returned to datarequest.transplantlines@umcg.nl, after which the request will be approved or rejected based on scien...

Conditions
  • health or medical or biomedical research
  • disease specific research
Linkage options

NITRA, NOTR, PALGA, among others. We are continuously working to increase the linkage options with additional data sources.

Funding & Citation requirements

Funding

The TransplantLines Biobank and Cohort Study was supported by unrestricted grants from Astellas BV and Chiesi Pharmaceuticals BV. In addition, this collaboration project is co-financed by the Dutch Ministry of Economic Affairs and Climate Policy by means of the PPP-allowance made available by the Top Sector Life Sciences & Health to stimulate public-private partnerships.